Abstract
This case study highlights the successful recruitment strategies employed by a clinical trials unit in South Africa during a challenging Chronic Obstructive Pulmonary Disease (COPD) treatment trial. Despite the trial’s global nature and the inherent difficulties in recruiting participants for COPD studies, the site emerged as a top recruiter. The Principal Investigator (PI) and Study Coordinator’s expertise in implementing effective recruitment methods led to their invitation to a global meeting, where they shared valuable insights with other trial sites.
Background
The clinical trial in question aimed to assess the efficacy and safety of a novel COPD treatment. With multiple sites worldwide, the trial faced difficulties in recruiting an adequate number of participants. The South African site, however, excelled in overcoming recruitment challenges, earning recognition as one of the top-performing sites.
Methods
- Community Engagement:
The site initiated extensive community engagement programs, collaborating with local healthcare providers, community leaders, and patient advocacy groups. - Cultural Sensitivity:
Tailored recruitment materials were developed, considering the cultural and linguistic diversity of the population. - Multi-disciplinary Approach:
Collaborative efforts involving internists, primary care physicians, and respiratory clinic staff enhanced the site’s ability to identify eligible participants. - Patient-Centric Approach:
Clear communication of potential benefits and risks ensured informed decision-making by participants.
Results
TASK’s recruitment success was evident in the enrolment numbers exceeding expectations. The PI and Study Coordinator’s commitment to excellence contributed to their invitation to a global meeting of trial sites.
Global Meeting Contribution
At the global meeting, the South African team shared their successful recruitment strategies, emphasizing the importance of community engagement, cultural sensitivity, and a patient-centric approach. The PI and Study Coordinator participated in discussions, providing valuable insights and practical advice for overcoming recruitment challenges in diverse healthcare settings.
Conclusion
This case study highlights the effectiveness of tailored recruitment strategies in the context of a challenging COPD treatment trial in South Africa. The site’s recognition as a top recruiter and the invitation to the global meeting underscore the importance of implementing innovative and culturally sensitive approaches in clinical trial recruitment. The lessons learned from this experience can inform future trials and contribute to the global advancement of COPD treatment research.